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A collection of human ligand-receptor interactions.

LRI_human.Rd

This dataset contains a data.table of curated human ligand-receptor interactions as well as related annotations (GO Terms, KEGG Pathways) and metadata.

Usage

data(LRI_human)

Format

A list with the following items:

  1. LRI_curated: a data.table of curated LRIs

  2. LRI_curated_GO: a data.table with GO terms attached to curated LRIs

  3. LRI_curated_KEGG: a data.table with KEGG pathways attached to curated LRIs

  4. LRI_retrieved_dates: dates at which data have been retrieved from the seven external databases

  5. LRI_retrieved_from: paths or packages from where data have been retrieved

  6. LRI_biomart_ensembl_version: version of ensembl used for GO annotation

Details

The dataset has been built internally in scDiffCom according to scDiffCom:::build_LRI(species = "human"). The LRIs have been retrieved from seven databases (see References). Note that only curated LRIs have been kept.

References

CellChat (PMID: 33597522), CellPhoneDB (PMID: 32103204), CellTalkDB (PMID: 33147626), connectomeDB2020 (PMID: 33024107), ICELLNET (PMID: 33597528), NicheNet (PMID: 31819264), SingleCellSignalR (PMID: 32196115)